Epinine
Epinine (also known as 3,4-dihydroxyphenethylamine) is a naturally occurring chemical compound found in the human body. It is a metabolite of the neurotransmitter dopamine, and plays a role in various physiological processes.
Chemistry[edit | edit source]
Epinine is a member of the class of compounds known as phenethylamines, which are organic compounds containing a phenethyl group. It is a monoamine, a type of molecule that contains one amino group connected to an aromatic ring by a two-carbon chain. Epinine is also a catecholamine, a type of monoamine that contains a catechol group.
Biosynthesis[edit | edit source]
Epinine is synthesized in the body from dopamine by the enzyme dopamine beta-hydroxylase. This enzyme catalyzes the conversion of dopamine to norepinephrine, with epinine as an intermediate product. The reaction requires oxygen and copper as cofactors.
Physiological role[edit | edit source]
Epinine acts as a neurotransmitter in the nervous system, where it is involved in transmitting signals between nerve cells. It is also involved in the regulation of heart rate and blood pressure, and plays a role in the body's response to stress.
Pharmacology[edit | edit source]
Epinine has been found to have vasoconstrictor effects, meaning it can cause the narrowing of blood vessels. This can increase blood pressure and reduce blood flow to certain areas of the body. It also has bronchodilator effects, meaning it can cause the airways in the lungs to widen, making it easier to breathe.
Research[edit | edit source]
Research into the role of epinine in the body and its potential therapeutic uses is ongoing. Some studies have suggested that it may have potential as a treatment for conditions such as hypotension (low blood pressure) and certain types of asthma.
See also[edit | edit source]
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