Deoxyepinephrine

Deoxyepinephrine, also known as Norepinephrine or Noradrenaline, is a hormone and neurotransmitter that plays a significant role in the body's stress response. It is produced in the adrenal medulla and is released into the bloodstream during times of physical or mental stress.

Function

Deoxyepinephrine functions as both a hormone and a neurotransmitter. As a hormone, it is released into the bloodstream by the adrenal medulla. As a neurotransmitter, it is used by nerve cells to send signals to other cells.

Deoxyepinephrine's primary function is to prepare the body for a 'fight or flight' response by increasing heart rate, blood pressure, and glucose levels. It also helps to narrow the blood vessels and open the airways, allowing for increased blood flow to the muscles and improved oxygen flow to the lungs.

Production

Deoxyepinephrine is produced in the adrenal medulla, a part of the adrenal gland. The production process begins with the amino acid tyrosine, which is converted into DOPA by the enzyme tyrosine hydroxylase. DOPA is then converted into dopamine, which is finally converted into deoxyepinephrine by the enzyme dopamine β-hydroxylase.

Role in Disease

Abnormal levels of deoxyepinephrine can lead to a number of health problems. High levels can cause hypertension, anxiety, and panic attacks, while low levels can lead to depression and orthostatic hypotension.

Treatment

Medications that affect the production or function of deoxyepinephrine are used to treat a variety of conditions. For example, beta blockers are used to treat hypertension by blocking the effects of deoxyepinephrine on the heart and blood vessels.

See Also

• Adrenaline
• Stress (biology)
• Neurotransmitter
• Hormone

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