Epithelial

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Epithelial is a type of tissue that lines the surfaces and cavities of the body's organs. It is one of the four main types of tissue, along with connective tissue, muscle tissue, and nervous tissue. Epithelial tissue is characterized by its lack of blood vessels, its cells' close proximity to each other, and its functions, which include protection, secretion, absorption, and filtration.

Structure[edit | edit source]

Epithelial tissue is composed of cells that are closely packed together with little intercellular material. These cells are often bound together by cell junctions, which provide a secure attachment among them. The cells are organized into a continuous sheet, either in a single or multiple layers.

The bottom layer of cells is attached to a basement membrane, a thin, fibrous structure that anchors the epithelium to the underlying connective tissue. This basement membrane provides support and also acts as a barrier against the movement of cells and large molecules.

Functions[edit | edit source]

Epithelial tissue has several key functions:

  • Protection: It forms a protective barrier that shields the body's internal structures from physical damage, harmful substances, and pathogenic organisms.
  • Secretion: Some epithelial cells are specialized to produce and release certain substances such as enzymes, hormones, and sweat.
  • Absorption: Certain types of epithelial tissue, such as that found in the intestines, are specialized for absorbing nutrients and other substances.
  • Filtration: In organs like the kidneys, epithelial tissue filters out waste products from the blood.

Types[edit | edit source]

Epithelial tissue is classified based on the number of cell layers and the shape of the cells.

  • Simple epithelium: This type has a single layer of cells. It is found in areas where absorption, secretion, and filtration occur.
  • Stratified epithelium: This type has multiple layers of cells and is found in areas that need to withstand physical or chemical wear and tear.
  • Pseudostratified epithelium: This type appears to have multiple layers due to the irregular placement of the nuclei, but all cells are in contact with the basement membrane.
  • Transitional epithelium: This type can stretch and change shape. It is found in organs like the bladder that need to expand and contract.

Based on cell shape, epithelial tissue can be squamous (flat), cuboidal (cube-shaped), or columnar (tall and cylindrical).

Diseases[edit | edit source]

Diseases of the epithelial tissue include cancer, inflammation, and infections. Epithelial cells can also be damaged by physical trauma, burns, or exposure to harmful substances.

Epithelial Resources
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Contributors: Prab R. Tumpati, MD, Dr.T