Stratified squamous epithelium

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Stratified Squamous Epithelium[edit | edit source]

Stratified squamous epithelium is a type of epithelial tissue characterized by multiple cell layers, with cells becoming increasingly flattened towards the surface and more cuboidal near the base.

Micrograph of stratified squamous epithelium.

Overview[edit | edit source]

This type of epithelium is designed for protection, found in areas subject to abrasion or friction. It plays a vital role in defending against microbial and physical assaults.

Structure[edit | edit source]

The stratified squamous epithelium is composed of several layers:

  • Basal layer: Consisting of cuboidal cells, responsible for continual cell production.
  • Intermediate layers: Cells start to flatten as they move upwards.
  • Surface layers: Composed of flattened, dead cells, often keratinized in areas like the skin.

Locations and Functions[edit | edit source]

  • Skin: Provides a barrier against pathogens, mechanical injury, and fluid loss.
  • Oral cavity, esophagus, and vagina: Non-keratinized form, providing a moist, protective layer.

Cell Differentiation and Renewal[edit | edit source]

Cells in the basal layer continually divide, pushing older cells towards the surface. This process leads to cell differentiation and ultimately the formation of a protective, flattened layer.

Diagram showing layers of the skin, including stratified squamous epithelium.

Pathology[edit | edit source]

Abnormalities in this epithelium can lead to various conditions, including skin cancer, Psoriasis, and Lichen Planus.

Research and Studies[edit | edit source]

Ongoing research aims to understand how this epithelium responds to damage and how it regenerates, which is crucial for developing treatments for skin and mucosal diseases.

See Also[edit | edit source]

External Links[edit | edit source]

References[edit | edit source]

Stratified squamous epithelium Resources
Wikipedia



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