Eprosartan
Information about Eprosartan[edit source]
Eprosartan is an angiotensin II receptor blocker used in the therapy of hypertension.
Liver safety of Eprosartan[edit source]
Eprosartan is associated with a low rate of transient serum aminotransferase elevations but has yet to be linked to instances of acute liver injury.
Mechanism of action of Eprosartan[edit source]
Eprosartan (ep" roe sar' tan) is an angiotensin II receptor blocker (ARB) used alone or in combination with other agents for therapy of hypertension. Eprosartan inhibits the renin-angiotensin system by blocking the angiotensin II type 1 receptor (AT1), which prevents the vasoconstriction and volume expansion induced by circulating angiotensin II thus accounting for its antihypertensive activity.
FDA approval information for Eprosartan[edit source]
Eprosartan was approved for use in the United States in 1997 for the treatment of hypertension.
Dosage and administration for Eprosartan[edit source]
Eprosartan is available in 400 and 600 mg tablets generically and under the trade name Teveten. The typical dose in adults in 400 to 800 mg daily in one or two divided doses, and it is used long term. Eprosartan is also available in fixed combinations with hydrochlorothiazide (Teveten HCT).
Side effects of Eprosartan[edit source]
Side effects are uncommon, but can include headache, dizziness, fatigue, edema, cough, gastrointestinal upset, and fetal toxicity. Many ARBs including eprosartan have been linked to rare instances of a severe sprue-like enteropathy that presents with chronic diarrhea and weight loss and villous flattening and atrophy on intestinal biopsy. The diarrhea usually arises after 6 months or more of therapy and does not respond to corticosteroids or a gluten-free diet, but does resolve promptly with stopping eprosartan. This adverse side effect is most common wtih olmesartan.
The common ARBS are the following:
Common ACE inhibitors include the following:
- Benazepril
- Captopril
- Enalapril
- Fosinopril
- Lisinopril
- Moexipril
- Perindopril
- Quinapril
- Ramipril
- Trandolapril
| Eprosartan Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
