Esprolol

Esprolol is a beta blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It is also used to reduce mortality following a myocardial infarction. Esprolol works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Pharmacology[edit | edit source]

Esprolol is a selective beta-1 adrenergic receptor antagonist, which means it specifically blocks the beta-1 adrenergic receptors in the heart, without significantly affecting the beta-2 receptors in the lungs and vascular smooth muscle. This selectivity makes it safer for use in patients with asthma or COPD, as it is less likely to cause bronchospasm.

Clinical Use[edit | edit source]

Esprolol is used to treat a variety of cardiovascular conditions. It is commonly used to manage hypertension, or high blood pressure, by reducing the heart rate and the force of the heart muscle contraction, thereby reducing the heart's demand for oxygen.

In patients with angina pectoris, esprolol helps to prevent angina attacks by reducing the workload of the heart and decreasing the amount of oxygen the heart needs.

Esprolol is also used to treat or prevent heart attack. It is beneficial in patients with a recent myocardial infarction, as it can help to prevent additional heart attacks and increase the chances of survival.

Side Effects[edit | edit source]

Like all medications, esprolol can cause side effects. Common side effects include bradycardia, hypotension, fatigue, and dizziness. Less common side effects can include shortness of breath, insomnia, and depression.