Estradiol dicypionate
Estradiol dicypionate (EDC), also known as estradiol cypionate, is a estrogen that is used in hormone therapy. It is a form of estradiol, the primary female sex hormone, and is used to treat a variety of conditions related to hormone imbalances or deficiencies.
Pharmacology[edit | edit source]
Estradiol dicypionate is a prodrug of estradiol, meaning it is metabolized in the body into estradiol. It is an estrogen ester, specifically the 3-cyclopentylpropanoyl ester of estradiol. As an estrogen, it has both agonist and antagonist effects on various estrogen receptors throughout the body.
Medical uses[edit | edit source]
Estradiol dicypionate is used in hormone therapy for menopausal symptoms, hypogonadism, osteoporosis, and for feminizing hormone therapy for transgender women. It is also used in veterinary medicine.
Side effects[edit | edit source]
Like all estrogens, estradiol dicypionate can have a number of side effects, including nausea, bloating, breast tenderness, and an increased risk of thrombosis and breast cancer.
History[edit | edit source]
Estradiol dicypionate was first described in the medical literature in 1952 and was introduced for medical use in the United States in 1954.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD