Estradiol phosphate

Estradiol phosphate is a steroid and estrogen that is used in hormone therapy. It is a prodrug of estradiol, and when administered into the body, it is converted into estradiol. Estradiol phosphate is used in the treatment of menopausal symptoms, hormone-sensitive cancers, and in hormone replacement therapy for transgender women.

Pharmacology

Estradiol phosphate is a prodrug of estradiol, meaning it is metabolized into estradiol in the body. It is administered via intramuscular injection, and has a longer duration of action compared to estradiol. This is due to the slow release of estradiol from the injection site, and the slow conversion of estradiol phosphate into estradiol.

Medical uses

Estradiol phosphate is used in the treatment of menopausal symptoms such as hot flashes and vaginal dryness. It is also used in the treatment of hormone-sensitive cancers such as breast cancer and prostate cancer. In addition, estradiol phosphate is used in hormone replacement therapy for transgender women, to help them develop secondary sexual characteristics.

Side effects

Like all estrogens, estradiol phosphate can have side effects. These can include nausea, breast tenderness, and an increased risk of blood clots. Long-term use of estradiol phosphate can also increase the risk of endometrial cancer and breast cancer.

See also

• Estradiol
• Prodrug
• Hormone therapy
• Menopause
• Transgender hormone therapy

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