Etacstil
Etacstil is a chemical compound with the formula C20H24N2O2. It is a synthetic nonsteroidal estrogen that was never marketed. The compound is part of the diethylstilbestrol group, and is structurally related to stilbestrol and dienestrol.
Chemistry[edit | edit source]
Etacstil is a synthetic, nonsteroidal estrogen of the stilbestrol group that is related to diethylstilbestrol. It is a white to off-white crystalline powder that is soluble in ethanol and acetone, but insoluble in water. The compound has a molecular weight of 324.42 g/mol.
Pharmacology[edit | edit source]
As an estrogen, etacstil binds to and activates the estrogen receptor (ER), specifically ERα and ERβ. This results in the transcription of genes that are regulated by these receptors, leading to the production of proteins that mediate the effects of estrogen in the body. The exact mechanism of action of etacstil is not fully understood, but it is thought to involve the regulation of gene expression in target tissues.
History[edit | edit source]
Etacstil was first synthesized in the 1970s as part of a series of compounds designed to study the structure-activity relationships of nonsteroidal estrogens. Despite showing promising activity in preclinical studies, the compound was never developed for clinical use.
See also[edit | edit source]
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