Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin. It is similar in structure to ephedrine, and acts as a sympathomimetic.
Pharmacology[edit | edit source]
Etafedrine is a bronchodilator and a vasodilator that is used to relieve bronchial spasms. It is a sympathomimetic drug that acts on the adrenergic receptor system, particularly the beta-2 adrenergic receptor, which is responsible for smooth muscle relaxation in the bronchial tubes and vasculature.
Chemistry[edit | edit source]
Etafedrine is a phenethylamine derivative, and is structurally similar to ephedrine. It is a chiral compound, and is used in medicine as a racemate, an equal mixture of the two enantiomers.
Medical uses[edit | edit source]
Etafedrine is used in the treatment of asthma and other conditions involving bronchospasm. It is not commonly used, but is considered a second-line treatment when other bronchodilators such as salbutamol (albuterol) are not effective.
Side effects[edit | edit source]
Like other sympathomimetic drugs, etafedrine can cause side effects such as tachycardia, hypertension, and palpitations. It can also cause nervousness, insomnia, and tremors.
See also[edit | edit source]
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