Express
Express is a term often used in the field of genetics and molecular biology to denote the process by which the information encoded in a gene is used to produce a functional product, such as a protein. This process involves two main steps: transcription and translation.
Transcription[edit | edit source]
Transcription is the first step in gene expression. It involves the synthesis of an RNA molecule that is complementary to the DNA strand of the gene. This process is carried out by an enzyme called RNA polymerase.
Translation[edit | edit source]
Translation is the second step in gene expression. It involves the synthesis of a protein molecule based on the sequence of the RNA molecule produced during transcription. This process is carried out by ribosomes, which are complex molecular machines that read the RNA sequence and assemble the corresponding protein.
Regulation of Gene Expression[edit | edit source]
The process of gene expression is tightly regulated by the cell. This regulation can occur at various stages, including at the level of transcription, RNA processing, translation, and post-translational modifications. The mechanisms of gene regulation are complex and involve a variety of proteins and RNA molecules.
Clinical Significance[edit | edit source]
Abnormalities in gene expression can lead to a variety of diseases, including cancer, autoimmune diseases, and genetic disorders. Understanding the mechanisms of gene expression and its regulation is therefore crucial for the development of new treatments for these diseases.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD