Dysplastic nevus syndrome

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(Redirected from FAMMM syndrome)

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Dysplastic nevus syndrome
Synonyms Familial atypical multiple mole melanoma syndrome (FAMMM)
Pronounce N/A
Specialty N/A
Symptoms Multiple atypical moles, increased risk of melanoma
Complications Melanoma, skin cancer
Onset Usually in adolescence or early adulthood
Duration Lifelong
Types N/A
Causes Genetic mutations, often in the CDKN2A gene
Risks Family history of melanoma, fair skin, excessive sun exposure
Diagnosis Skin examination, biopsy
Differential diagnosis Common mole, melanoma, seborrheic keratosis
Prevention Regular skin checks, sun protection
Treatment Monitoring, surgical removal of suspicious moles
Medication N/A
Prognosis Variable, depends on early detection and management
Frequency Rare, but more common in families with a history of melanoma
Deaths N/A


Dysplastic nevus syndrome is a medical condition characterized by the presence of multiple atypical moles (dysplastic nevi) on the skin. These moles have irregular features under the microscope and may be larger than ordinary moles. People with dysplastic nevus syndrome have a higher risk of developing melanoma, a serious type of skin cancer.

Causes[edit]

The exact cause of dysplastic nevus syndrome is unknown. However, it is believed to be due to a combination of genetic and environmental factors. A family history of the condition or of melanoma increases the risk.

Symptoms[edit]

People with dysplastic nevus syndrome have multiple atypical moles on their skin. These moles may be larger than ordinary moles and have irregular features under the microscope. They may also change in size, shape, or color over time.

Diagnosis[edit]

Diagnosis of dysplastic nevus syndrome is based on the clinical appearance of the moles and a history of atypical moles in the patient or their family. A skin biopsy may be performed to examine the mole under the microscope and confirm the diagnosis.

Treatment[edit]

There is no cure for dysplastic nevus syndrome. However, regular skin examinations can help detect changes in the moles early and reduce the risk of developing melanoma. In some cases, atypical moles may be removed to prevent them from becoming cancerous.

Prognosis[edit]

With regular skin examinations and early detection of changes in the moles, the prognosis for people with dysplastic nevus syndrome is generally good. However, they have a higher risk of developing melanoma and should be monitored closely.

See also[edit]

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