FERM and PDZ domain containing 2
FERM and PDZ domain containing 2 (also known as FRMPD2) is a protein that in humans is encoded by the FRMPD2 gene. This protein is a member of the FERM domain family, and also contains a PDZ domain.
Function[edit | edit source]
The FRMPD2 protein is a member of the FERM domain family, named for the four proteins in which it was originally identified: 4.1 protein, ezrin, radixin, and moesin. These proteins are involved in the linkage of the cytoskeleton to the plasma membrane, playing a crucial role in maintaining cell shape and integrity.
The PDZ domain in FRMPD2 is a common structural domain in signaling proteins. PDZ domains bind to the C-terminus of other proteins, playing a role in the assembly of protein complexes at the cell membrane.
Clinical significance[edit | edit source]
While the exact role of FRMPD2 in human health and disease is not fully understood, alterations in FERM and PDZ domain proteins have been implicated in a variety of diseases, including cancer, neurological disorders, and cardiovascular diseases.
See also[edit | edit source]
References[edit | edit source]
 | This protein-related article is a stub. You can help WikiMD by expanding it. |
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
