FLEA (psychedelic)

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FLEA (2-Fluoroethylamphetamine) is a psychedelic drug and a substituted amphetamine that has been known in the research chemical market. It is a lesser-known compound within the realm of psychoactive substances, and its effects, pharmacology, and toxicity are not well understood. Due to its structural similarity to amphetamine and other psychedelic phenethylamines, it is presumed to act primarily as a serotonin, dopamine, and norepinephrine releasing agent or reuptake inhibitor, which could account for its psychoactive effects. However, the exact mechanism of action remains speculative without further scientific study.

Chemistry[edit | edit source]

FLEA is a member of the phenethylamine class, sharing a core structure with other phenethylamines, which includes a phenyl ring bound to an amino (NH2) group through an ethyl chain. FLEA differs from amphetamine by the addition of a fluorine atom at the beta position of the ethyl chain, which is believed to affect its pharmacokinetics and potency. The presence of the fluorine atom can significantly alter the lipophilicity of the compound, potentially affecting its ability to cross the blood-brain barrier and its overall psychoactive profile.

Pharmacology[edit | edit source]

While the pharmacological profile of FLEA has not been extensively studied, it is hypothesized to work by increasing the release of monoamines such as serotonin, dopamine, and norepinephrine in the brain or by inhibiting their reuptake. This action is similar to that of other psychoactive phenethylamines, contributing to their effects on mood, perception, and cognition. However, the specific effects of FLEA, including its efficacy and safety, remain largely unknown due to the lack of scientific research.

Effects[edit | edit source]

The subjective effects of FLEA are presumed to include euphoria, altered states of consciousness, and visual hallucinations, akin to other psychedelics and stimulants. However, these effects are largely anecdotal, coming from individual self-reports rather than controlled studies. The duration, intensity, and nature of these effects can vary widely depending on the dose, individual physiology, and other factors.

Toxicity and Harm Potential[edit | edit source]

The toxicity and long-term health effects of FLEA in humans are not well documented. Like other research chemicals, there is a lack of information on the safety profile of FLEA, and it is potentially hazardous to human health. Users should approach with caution, keeping in mind the potential for acute and chronic harm, including the possibility of addiction and psychological dependence.

Legal Status[edit | edit source]

The legal status of FLEA varies by country, but it may be considered illegal or controlled under analog acts due to its structural similarities to other regulated substances. Potential users should be aware of their local laws before attempting to obtain or use FLEA.

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Contributors: Prab R. Tumpati, MD