FTIR

From WikiMD's Food, Medicine & Wellness Encyclopedia

FTIR or Fourier Transform Infrared Spectroscopy is a technique used in chemistry and physics to obtain an infrared spectrum of absorption, emission, photoconductivity or Raman scattering of a solid, liquid or gas. It is a powerful tool for identifying types of chemical bonds in a molecule by producing an infrared absorption spectrum that is like a molecular "fingerprint".

History[edit | edit source]

The development of FTIR started in the 1950s with the aim to overcome the speed limitations of the dispersive spectrometers. It was commercially available in the 1960s and has since been widely used in the fields of chemistry, physics, and materials science.

Principle[edit | edit source]

FTIR works on the principle of Fourier Transform which is a mathematical process used to transform raw data into the actual spectrum. The sample is irradiated with all relevant wavelengths of infrared light at once and the absorption pattern is measured. This pattern is then transformed into an absorption spectrum using a mathematical algorithm.

Applications[edit | edit source]

FTIR is used in a wide range of applications including:

  • Chemical analysis: FTIR can identify unknown materials, detect the quality or consistency of a sample, and determine the amount of components in a mixture.
  • Pharmaceutical industry: It is used for quality control, to detect counterfeit drugs, and to monitor changes in drug properties.
  • Environmental science: FTIR can measure concentrations of gases in the atmosphere, helping to monitor and control air pollution.
  • Forensic science: It can identify substances found at a crime scene, such as fibers, paints, and drugs.

Advantages and Disadvantages[edit | edit source]

Advantages of FTIR include its speed, the ability to analyze a wide range of samples, and the fact that it is non-destructive. However, it can be less accurate than other methods for quantitative analysis, and it requires a relatively large amount of sample.

See Also[edit | edit source]

References[edit | edit source]


FTIR Resources
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Contributors: Prab R. Tumpati, MD