FAP
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Familial Adenomatous Polyposis (FAP) is a rare, inherited condition characterized by the development of many (hundreds to thousands) polyps (adenomas) in the lining of the colon and rectum. People with FAP have a greatly increased risk of developing colorectal cancer at a young age.
Symptoms[edit | edit source]
The symptoms of FAP can vary and may include:
- Abdominal pain
- Diarrhea
- Rectal bleeding
- Anemia due to chronic bleeding
Causes[edit | edit source]
FAP is caused by mutations in the APC gene. This gene provides instructions for making a protein that plays a critical role in several cellular processes. The protein helps control how often a cell divides, how it attaches to other cells within a tissue, and whether it moves within or away from a tissue.
Diagnosis[edit | edit source]
FAP is diagnosed through a combination of physical examination, medical history, and genetic testing. Other tests that can help diagnose FAP include:
Treatment[edit | edit source]
Treatment for FAP may involve surgery to remove the colon and rectum, medication to reduce the number of polyps, and regular screening to detect polyps and cancer early.
See also[edit | edit source]
References[edit | edit source]
FAP Resources | ||
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