Fay and Wu's H
- Fay and Wu's H is a statistical test created by and named after two researchers Justin Fay and Chung-I Wu. The purpose of the test is to distinguish between a DNA sequence evolving randomly ( eutrally) and one evolving under positive selection. This test is an advancement over Tajima's D, which is used to differentiate neutrally evolving sequences from those evolving non-randomly (through directional selection or balancing selection, demographic expansion or contraction or genetic hitchhiking). Fay and Wu's H is frequently used to identify sequences which have experienced selective sweeps in their evolutionary history. [[Category:Uncategorized
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Contributors: Prab R. Tumpati, MD
