Fenofibrate/simvastatin

From WikiMD's Food, Medicine & Wellness Encyclopedia

Fenofibrate/Simvastatin is a combination medication used in the treatment of high cholesterol and triglyceride levels. It contains two active ingredients: Fenofibrate and Simvastatin.

Etymology[edit | edit source]

The term "Fenofibrate" is derived from the chemical name "fenofibric acid", while "Simvastatin" is derived from the chemical name "simvastatin acid". Both names are derived from their respective chemical structures.

Pharmacology[edit | edit source]

Fenofibrate is a type of drug known as a fibrate, which works by reducing the levels of triglycerides and low-density lipoprotein (LDL) cholesterol in the blood, while increasing levels of high-density lipoprotein (HDL) cholesterol. Simvastatin is a statin, which works by inhibiting the enzyme HMG-CoA reductase, thereby reducing the production of cholesterol in the liver.

Indications[edit | edit source]

Fenofibrate/Simvastatin is indicated for the treatment of high cholesterol and triglyceride levels. It is used in conjunction with a low-fat diet and exercise to reduce the risk of heart disease and stroke.

Side Effects[edit | edit source]

Common side effects of Fenofibrate/Simvastatin include headache, stomach pain, and muscle pain. Serious side effects may include liver damage, kidney damage, and a rare but serious muscle condition known as rhabdomyolysis.

Related Terms[edit | edit source]

See Also[edit | edit source]

Fenofibrate/simvastatin Resources
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Contributors: Prab R. Tumpati, MD