Fight or flight

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Fight or flight

The fight or flight response, also known as the acute stress response, is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival. This concept was first described by Walter Bradford Cannon, an American physiologist, in the early 20th century. It represents a fundamental mechanism in the animal kingdom, including humans, enabling the organism to rapidly mobilize energy and resources to either fight or flee from a threat.

Overview[edit | edit source]

The fight or flight response is triggered by the release of hormones that prepare the body to either stay and deal with a threat or to run away to safety. The key hormones involved are adrenaline (epinephrine) and norepinephrine (noradrenaline), which are produced by the adrenal glands. Upon encountering a threat, these hormones cause various physiological changes in the body, such as increased heart rate, increased blood pressure, dilated pupils, and increased blood flow to muscles, thereby preparing the body for a rapid, intense physical response.

Physiological Changes[edit | edit source]

The physiological changes that occur during the fight or flight response include:

  • Increased heart rate and blood pressure: to supply muscles with more oxygen and nutrients.
  • Dilated pupils: to improve vision.
  • Redistribution of blood flow from non-essential to essential areas: prioritizing muscles and critical organs.
  • Increased blood glucose levels: to provide more energy.
  • Suppression of non-essential functions: such as digestion and immune system activity.

These changes are mediated by the sympathetic nervous system and are designed to maximize the body's ability to respond to a threat. However, in modern society, where physical threats are less common, this response can be triggered by situations that are not life-threatening, such as stress at work or personal conflicts, leading to chronic stress and related health issues.

Psychological Aspects[edit | edit source]

The fight or flight response not only involves physical changes but also has psychological components. The perception of a threat can significantly influence the intensity of the response. Cognitive processes, such as the assessment of danger and the decision-making process regarding the best course of action (fight or flee), play a crucial role in this response.

Evolutionary Perspective[edit | edit source]

From an evolutionary perspective, the fight or flight response has been crucial for the survival of species. It enables organisms to quickly respond to immediate threats, increasing their chances of survival. However, the modern human environment has evolved much faster than our biological response mechanisms, leading to situations where the fight or flight response can be triggered inappropriately, causing unnecessary stress and anxiety.

Clinical Implications[edit | edit source]

The chronic activation of the fight or flight response, due to ongoing stress or anxiety, can have detrimental effects on health. It is associated with a range of conditions, including heart disease, diabetes, anxiety disorders, and depression. Understanding and managing the triggers of this response is crucial for mental and physical health.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD