Diflorasone diacetate

Diflorasone diacetate is a corticosteroid used in the treatment of various skin disorders. It is a synthetic, high-potency topical corticosteroid that exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties.

Pharmacology

Diflorasone diacetate works by reducing the actions of chemicals in the body that cause inflammation, redness, and swelling. It is a glucocorticoid receptor agonist. The exact mechanism of how diflorasone diacetate works is not fully understood. However, it is believed to act by inducing phospholipase A2 inhibitory proteins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Medical uses

Diflorasone diacetate is used to treat a variety of skin conditions, including psoriasis, eczema, dermatitis, allergies, and rash. It is applied topically to the skin to relieve redness, swelling, itching, and discomfort of various skin conditions.

Side effects

Like all medicines, diflorasone diacetate can cause side effects, although not everybody gets them. Common side effects include burning, itching, irritation, dryness, and folliculitis. More serious side effects may include skin thinning, stretch marks, and skin color changes.

Precautions

Before using diflorasone diacetate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

See also

• List of corticosteroids
• Topical steroid