Fluspirilene
Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, sold under the brand name Imap among others. It is classified as a typical antipsychotic and is used in the treatment of schizophrenia and other psychotic disorders.
Etymology[edit | edit source]
The term "Fluspirilene" is derived from its chemical structure, which consists of a fluoro group (Flu-), a spirane (spir-), and a piperidine (-ilene).
Pharmacology[edit | edit source]
Fluspirilene is a long-acting, injectable depot antipsychotic. It is a potent D2 receptor antagonist and also has high affinity for the D1 receptor. It has moderate affinity for the 5-HT2A receptor and low affinity for the 5-HT2C receptor.
Clinical Use[edit | edit source]
Fluspirilene is used primarily in the treatment of schizophrenia. It is also used in the treatment of other psychotic disorders, including bipolar disorder, paranoid disorder, and schizoaffective disorder.
Side Effects[edit | edit source]
Like other typical antipsychotics, fluspirilene can cause a range of side effects. These can include extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome, and anticholinergic effects.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
