Fluticasone furoate/vilanterol

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Fluticasone furoate and vilanterol

Fluticasone furoate/vilanterol is a combination medication used in the management and treatment of asthma and chronic obstructive pulmonary disease (COPD). This combination includes fluticasone furoate, a corticosteroid, and vilanterol, a long-acting beta-adrenoceptor agonist (LABA). The medication works by reducing inflammation in the lungs and relaxing the muscles around the airways, making breathing easier for patients.

Composition

Fluticasone furoate/vilanterol combines two active ingredients:

• Fluticasone furoate: A synthetic corticosteroid with potent anti-inflammatory properties. It works by inhibiting multiple cell types and mediators involved in allergic, inflammatory, and immune responses.
• Vilanterol: A long-acting beta-adrenoceptor agonist that helps to relax the muscles around the airways in the lungs, which can prevent symptoms such as wheezing, coughing, chest tightness, and shortness of breath.

Indications

This combination medication is indicated for:

• The maintenance treatment of asthma in patients aged 12 years and older.
• The long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

Dosage and Administration

Fluticasone furoate/vilanterol is administered via inhalation only, using a specific inhaler device. The dosage and frequency of use depend on the condition being treated and the patient's response to therapy. It is important for patients to use this medication regularly to get the most benefit from it. Patients should also follow their healthcare provider's instructions carefully regarding the use of the inhaler device.

Side Effects

Common side effects of fluticasone furoate/vilanterol may include:

• Headache
• Nasopharyngitis (common cold)
• Bronchitis
• Pharyngitis
• Influenza
• Back pain

Patients should seek medical attention if they experience severe side effects such as signs of a serious allergic reaction, chest pain, increased blood pressure, or symptoms of a fungal infection in the mouth or throat.

Precautions

Patients with a history of severe allergies to milk proteins or any ingredient in the medication should not use fluticasone furoate/vilanterol. It is also not intended for the relief of acute bronchospasm or as a primary treatment for asthma or COPD. Patients should be assessed regularly by their healthcare provider to determine if the medication is working effectively and if adjustments to the treatment plan are necessary.

Interactions

Fluticasone furoate/vilanterol may interact with other medications, which can affect how it works or increase the risk of serious side effects. Patients should inform their healthcare provider about all the drugs they are taking, including prescription drugs, over-the-counter medications, and herbal products.

Conclusion

Fluticasone furoate/vilanterol is an effective combination medication for the treatment of asthma and COPD, offering the benefits of both a corticosteroid and a LABA. Proper use under the guidance of a healthcare provider can help manage symptoms and improve the quality of life for patients with these chronic respiratory conditions.