FlyBase

FlyBase is a comprehensive database for information on the genetics and molecular biology of the fruit fly, Drosophila melanogaster. It is a critical resource for researchers in the field of genomics, bioinformatics, and developmental biology.

History

FlyBase was established in the early 1990s as a collaborative effort among several Drosophila research groups. The database has grown significantly over the years, incorporating a wide range of data types and providing tools for data analysis and visualization.

Features

FlyBase offers a variety of features to support the research community:

• Genomic Data: FlyBase provides detailed information on the genome of Drosophila melanogaster, including gene sequences, gene expression, and gene function.
• Mutant Alleles: Information on various mutant alleles and their phenotypic effects.
• Gene Ontology: Annotations related to Gene Ontology (GO) terms, which describe gene products in terms of their associated biological processes, cellular components, and molecular functions.
• Pathways: Data on biological pathways and interactions.
• Tools: A suite of tools for data analysis, including BLAST, GBrowse, and JBrowse.

Data Sources

FlyBase integrates data from multiple sources, including:

• GenBank
• PubMed
• Gene Ontology Consortium
• InterPro
• Reactome

Community Involvement

FlyBase is maintained by a consortium of Drosophila researchers and bioinformaticians. The database is continuously updated with new data and tools, and the community is encouraged to contribute by submitting new data and annotations.

Access

FlyBase is freely accessible to the public and can be accessed through its website. The database provides various search and browse options to facilitate easy access to the information.

See Also

• Drosophila melanogaster
• Genomics
• Bioinformatics
• Gene Ontology
• BLAST
• GBrowse
• JBrowse