Fragile site
Fragile site - heritable sensitive regions of chromosomes which show up in vitro as non-staining bands. They are associated with chromosome breakage and other aberrations. No abnormal phenotype has been definitely identified with autosomal fragile sites, but some rare autosomal recessive disorders may be due to homozygosity for fragile sites. A fragile site on the x chromosome is associated with fragile x syndrome. Fragile sites are designated by the letters "Fra" followed by the designation for the specific chromosome and locus.
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Fragile site for any updates.
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