Tandem mass spectrometry
(Redirected from Fragment ion)
Tandem mass spectrometry (also known as MS/MS or MS2) is a method used in analytical chemistry to identify the quantity and type of individual chemical compounds in a sample. It involves multiple steps of mass spectrometry and some form of fragmentation.
Overview[edit | edit source]
In a tandem mass spectrometry process, ions are formed in the ion source and are then subjected to a first stage of mass spectrometry to separate them by their mass-to-charge ratio. The selected ions are then fragmented and the fragments are subjected to a second stage of mass spectrometry to further separate them. The resulting spectrum is then used to identify the original molecule.
Applications[edit | edit source]
Tandem mass spectrometry is used in many different fields, including biochemistry, pharmacology, and environmental science. It is particularly useful in proteomics, where it is used to identify proteins and to determine their sequences. It is also used in metabolomics to identify small molecules.
See also[edit | edit source]
References[edit | edit source]
Tandem mass spectrometry Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD