Fursultiamine

Fursultiamine (INN: Adventan, Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor), commonly identified as thiamine tetrahydrofurfuryl disulfide (TTFD), is an allithiamine or a disulfide derivative of thiamine.

History[edit | edit source]

Fursultiamine was initially synthesized in Japan during the 1960s with the intention of formulating variants of thiamine that exhibited enhanced lipophilicity. This was aimed at addressing and treating vitamin B1 deficiencies, specifically beriberi. Following its synthesis, it was subsequently commercialized in several countries including Japan, Spain, Austria, Germany, and the United States. Being a vitamin, it is also readily accessible over-the-counter.

Clinical Uses and Research[edit | edit source]

Apart from its primary indication to treat avitaminosis, fursultiamine has undergone clinical trials for potential use in the treatment of Alzheimer's disease and autistic spectrum disorders. While results indicated a certain level of benefit, they were deemed to be relatively modest. Fursultiamine has also been examined for its potential to enhance energy metabolism during exercise and mitigate exercise-induced fatigue. However, results from such studies have been inconclusive, showcasing both supporting and conflicting evidence.

Available Brands[edit | edit source]

Privitamix softgel (Available in India)

See also[edit | edit source]

Fursultiamine Resources
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