Fuselloviridae

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Fuselloviridae is a family of archaeal viruses that infects sulfolobus species. The family contains four genera: Alphafusellovirus, Betafusellovirus, Gammafusellovirus, and Deltafusellovirus.

Taxonomy[edit | edit source]

The family Fuselloviridae is divided into four genera:

  • Alphafusellovirus
  • Betafusellovirus
  • Gammafusellovirus
  • Deltafusellovirus

Each genus contains several species of viruses.

Structure[edit | edit source]

Fuselloviridae viruses are non-enveloped, with rod-shaped geometries. The diameter is around 55-60 nm, with a length of 90-100 nm. The viruses are composed of a lipid membrane, enclosing a circular, double-stranded DNA genome.

Life Cycle[edit | edit source]

Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. DNA-templated transcription is the method of transcription. The virus exits the host cell by lysis, and holin/endolysin/spanin proteins are involved. Sulfolobus species serve as the natural host.

Pathology[edit | edit source]

The pathology of Fuselloviridae is not well understood due to the extremophilic nature of their hosts. However, they are not known to cause disease in humans.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD