Genomic library

Genomic library is a collection of the total genomic DNA from a single organism. The DNA is stored in a population of identical vectors, each containing a different insert of DNA. In order to construct a genomic library, the organism's DNA is extracted from cells and then digested into fragments that can be inserted into the vector.

Overview[edit | edit source]

The genomic library contains all the sequences in the entire genome of an organism. It is different from a cDNA library in that it includes exons, introns, and noncoding sequences. The genomic library is a valuable tool in molecular biology research, as it allows for the study of gene structure, function, and evolution.

Construction[edit | edit source]

The construction of a genomic library involves several steps. First, the genomic DNA is extracted from the organism. This DNA is then fragmented, either by using restriction enzymes or by physical shearing. The resulting fragments are then inserted into a suitable vector. The vector is then introduced into a host organism, such as a bacterium, where it can replicate to produce many copies of the inserted DNA.

Applications[edit | edit source]

Genomic libraries are used in a variety of research applications. They can be used to map the genome of an organism, to identify and study specific genes, and to investigate the function of unknown genes. They are also used in comparative genomics, to compare the genomes of different species.

References[edit | edit source]

Genomic library Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.