Gliadin
Gliadin is a class of proteins present in wheat and several other cereals within the grass genus Triticum. Gliadins, which are a component of gluten, are essential for giving bread the ability to rise properly during baking. Gliadins and glutenins are the two main components of the gluten fraction of the wheat seed.
Overview[edit | edit source]
Gliadins are monomeric proteins that can be separated into four groups: alpha-, beta-, gamma-, and omega-gliadins. They are characterised by a high content of glutamine and proline. Gliadins are known to be the cause of Celiac disease (CD). In sensitive individuals, gliadins can induce an abnormal immune response that leads to CD.
Role in Celiac Disease[edit | edit source]
In individuals with CD, the body's immune system reacts to gliadin. When food containing the protein is consumed, the immune system launches an attack against it, which leads to damage to the small intestine. This damage inhibits the body's ability to absorb nutrients, leading to a variety of health problems.
Diagnosis and Treatment[edit | edit source]
Diagnosis of CD involves blood tests and biopsy of the small intestine. The only effective treatment is a lifelong gluten-free diet, which involves the avoidance of wheat, rye, barley and derivatives of these grains.
See Also[edit | edit source]
References[edit | edit source]
Gliadin Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD