Glisoxepide
Glisoxepide is a sulfonylurea antidiabetic drug that is used in the management of type 2 diabetes. It works by increasing the release of insulin from the pancreas, helping to control blood sugar levels.
Mechanism of Action[edit | edit source]
Glisoxepide, like other sulfonylureas, works by closing ATP-sensitive potassium channels in the beta cells of the Islets of Langerhans in the pancreas. This depolarizes the beta cells and opens voltage-gated calcium channels, allowing calcium to enter the cell. The increase in intracellular calcium stimulates the release of insulin.
Side Effects[edit | edit source]
Possible side effects of glisoxepide include hypoglycemia, nausea, vomiting, diarrhea, abdominal pain, and allergic reactions. In rare cases, it can cause liver damage or blood disorders.
Contraindications[edit | edit source]
Glisoxepide should not be used in patients with type 1 diabetes or diabetic ketoacidosis. It is also contraindicated in patients with severe liver disease or kidney disease, and in those who are allergic to sulfonylureas.
Interactions[edit | edit source]
Glisoxepide may interact with other medications, including beta blockers, warfarin, and phenytoin. It may also interact with alcohol, increasing the risk of hypoglycemia.
See Also[edit | edit source]
| Glisoxepide Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
