Glucose challenge test

From WikiMD's Food, Medicine & Wellness Encyclopedia

Glucose Challenge Test (GCT) is a screening procedure used to identify individuals who may have gestational diabetes, a type of diabetes mellitus that occurs during pregnancy. The test is typically conducted between the 24th and 28th weeks of pregnancy, although it may be performed earlier if a woman is considered at high risk for gestational diabetes.

Procedure[edit | edit source]

During the Glucose Challenge Test, the expectant mother is asked to drink a sweet liquid containing 50 grams of glucose. Blood is drawn one hour after the consumption of the glucose solution to measure the blood sugar level. If the blood sugar level is higher than the normal range, it indicates that the body is not efficiently using the glucose, which is a sign of gestational diabetes. In such cases, a follow-up test, known as the Glucose Tolerance Test (GTT), is recommended for a definitive diagnosis.

Indications[edit | edit source]

The GCT is recommended for all pregnant women as part of routine prenatal care. However, it is particularly important for those who have risk factors for gestational diabetes, such as:

  • A family history of diabetes
  • Obesity
  • Advanced maternal age (over 35)
  • A history of gestational diabetes in previous pregnancies
  • Polycystic ovary syndrome (PCOS)

Interpretation of Results[edit | edit source]

A blood sugar level below 140 mg/dL (7.8 mmol/L) is usually considered normal on the glucose challenge test. A blood sugar level higher than 140 mg/dL (7.8 mmol/L) indicates the need for further testing to determine if gestational diabetes is present.

Risks and Considerations[edit | edit source]

The Glucose Challenge Test is generally considered safe. The most common side effect is feeling nauseated or lightheaded after drinking the glucose solution. There is no risk to the fetus during the test.

Importance of Screening[edit | edit source]

Early detection and management of gestational diabetes are crucial to prevent complications during pregnancy and delivery. Uncontrolled gestational diabetes can lead to high birth weight, premature delivery, and respiratory distress syndrome in newborns. It can also increase the risk of the mother developing type 2 diabetes in the future.


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Contributors: Prab R. Tumpati, MD