Glycolytic
Glycolytic refers to the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− & H+. The free energy released in this process is used to form the high-energy molecules ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide).
Process[edit | edit source]
The glycolytic pathway can be divided into two phases:
- The Preparatory Phase – This phase consumes energy to convert the glucose into fructose 1,6-bisphosphate.
- The Pay Off Phase – This phase produces ATP and NADH.
Regulation[edit | edit source]
Glycolysis is regulated by three key enzymes: hexokinase, phosphofructokinase, and pyruvate kinase.
Clinical significance[edit | edit source]
Defects in glycolysis have been linked to different diseases including Pyruvate kinase deficiency, Glycogen storage disease type VII and Hemolytic anemia.
See also[edit | edit source]
References[edit | edit source]
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