Golgi complex

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Golgi Complex

The Golgi Complex, also known as the Golgi apparatus or simply the Golgi, is an organelle found in most eukaryotic cells. It was identified in 1897 by the Italian scientist Camillo Golgi, and is named after him.

Structure and Function[edit | edit source]

The Golgi complex is made up of a series of flattened, stacked pouches called cisternae. The structure of the Golgi complex is integral to its function, as it works primarily in the modification, sorting, and packaging of proteins for secretion. It is particularly important in the processing of proteins for secretion, producing a variety of vesicles that deliver these proteins to their destination.

Role in the Cell[edit | edit source]

The Golgi complex plays a crucial role in the transport of proteins within the cell. It acts as a 'sorting station' for proteins, modifying them and sending them to their correct destination. Proteins are transported to the Golgi complex in vesicles, where they are modified and packaged into new vesicles for transport to their final destination. This can include other parts of the cell, or the cell membrane for secretion out of the cell.

Clinical Significance[edit | edit source]

Defects in the function of the Golgi complex can lead to a number of diseases, including Alzheimer's disease, Parkinson's disease, and certain types of cancer. Understanding the function of the Golgi complex and its role in disease can help in the development of new treatments.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD