Golytely

Golytely

Golytely is a brand name for a type of bowel preparation solution used to cleanse the colon before a colonoscopy or other intestinal procedures. It is a polyethylene glycol (PEG) electrolyte solution that induces diarrhea to clear the intestines of fecal matter.

Composition

Golytely is composed of polyethylene glycol 3350, sodium sulfate, sodium bicarbonate, sodium chloride, and potassium chloride. This combination of ingredients works as an osmotic laxative, drawing water into the colon and promoting bowel movements.

Mechanism of Action

The primary mechanism of action of Golytely is through its osmotic effect. Polyethylene glycol is a large molecule that is not absorbed by the intestines. When ingested, it retains water in the bowel, increasing the water content of the stool and stimulating bowel movements. The electrolytes in the solution help maintain the body's electrolyte balance during the cleansing process.

Indications

Golytely is indicated for bowel cleansing prior to:

• Colonoscopy
• Barium enema
• Intestinal surgery

Administration

Golytely is typically administered orally. The standard regimen involves drinking the solution over a period of several hours, usually the day before the procedure. Patients are advised to follow a clear liquid diet on the day of the preparation to enhance the effectiveness of the bowel cleansing.

Side Effects

Common side effects of Golytely include:

• Nausea
• Bloating
• Abdominal cramping
• Vomiting

These side effects are generally mild and resolve after the bowel preparation is complete. Serious side effects are rare but can include electrolyte imbalances and dehydration.

Contraindications

Golytely is contraindicated in patients with:

• Gastrointestinal obstruction
• Bowel perforation
• Toxic colitis
• Toxic megacolon

Patient Instructions

Patients are typically instructed to: 1. Follow a clear liquid diet the day before the procedure. 2. Avoid solid foods, milk, and alcohol. 3. Drink the Golytely solution as prescribed, usually 240 mL every 10 minutes until the entire solution is consumed or bowel movements are clear.

Also see

• Colonoscopy
• Polyethylene glycol
• Laxative
• Electrolyte imbalance

Resources

Latest articles - Golytely

• Most recent articles
• Ongoing trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Golytely for any updates.

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