Guanidine
Guanidine is a compound with the formula HN=C(NH2)2. It is a colourless solid that dissolves in polar solvents. It is a strong base that is used in the production of plastics and explosives. It is found in urine as a normal product of protein metabolism. Guanidine is the compound with the highest pH value recorded.
Chemical Properties[edit | edit source]
Guanidine is a strong organic base, stronger than ammonia. It also acts as a nucleophile. The pKa of the guanidinium cation is 13.6. The related compound biguanide is also a potent base.
Uses[edit | edit source]
Guanidine is used in a variety of industrial applications, including as a plasticizer, a curing agent in epoxy resins, and a propellant for explosives. It is also used in the treatment of myasthenia gravis, a neuromuscular disease.
Health Effects[edit | edit source]
Exposure to guanidine can cause skin and eye irritation, and prolonged exposure can lead to more serious health effects such as respiratory distress and neurological damage.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
