HLA-B70
HLA-B70 is a human leukocyte antigen (HLA) serotype. The HLA system is a group of genes that are crucial for the function of the immune system. HLA-B70 is part of the HLA-B locus, which is a subcategory of the larger HLA system.
Function[edit | edit source]
HLA-B70 is involved in the presentation of antigens to the immune system. This is a crucial step in the immune response, as it allows the immune system to recognize and respond to foreign substances. The HLA-B70 molecule presents antigens to T cells, which then initiate an immune response.
Genetics[edit | edit source]
HLA-B70 is encoded by the HLA-B*70 allele group. This group contains two known alleles: HLA-B*7001 and HLA-B*7002. These alleles are relatively rare in the global population, with the highest frequencies found in certain ethnic groups in Africa and Asia.
Clinical significance[edit | edit source]
HLA-B70 has been associated with a number of diseases, including HIV infection and certain types of cancer. Studies have shown that individuals with the HLA-B*7002 allele may have a slower progression of HIV infection. However, more research is needed to fully understand the role of HLA-B70 in disease.
See also[edit | edit source]
References[edit | edit source]
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD