HLA-B72

HLA-B72 is a human leukocyte antigen (HLA) serotype. The HLA system is a group of genes that encode for proteins on the surface of cells that are responsible for regulation of the immune system. HLA-B72 is part of the HLA-B serotype group, which is located on the short arm of chromosome 6 (6p21.3).

Function

HLA-B72, like other HLA-B antigens, plays a crucial role in the immune system. It presents peptides (small proteins) from inside the cell to the immune system. If these peptides are derived from pathogens such as viruses or bacteria, the immune system will trigger a response to destroy the infected cells.

Association with Diseases

Certain HLA types are associated with an increased risk of specific diseases. However, as of now, there are no specific diseases associated with HLA-B72. Research is ongoing to determine if there are any associations.

Genetic Diversity

HLA-B72 is one of the many subtypes of the HLA-B gene. The HLA genes are the most diverse in the human genome, reflecting the need for the immune system to adapt to a wide range of pathogens.

See Also

• HLA-B
• Human leukocyte antigen
• Immune system
• Chromosome 6