Harry Goldblatt

[[File:"_prefix)-->|" prefix)-->|thumb]] Harry Goldblatt (1891–1977) was an American pathologist renowned for his pioneering research in the field of hypertension. His work significantly advanced the understanding of the mechanisms underlying high blood pressure and its effects on the body.

Early Life and Education

Harry Goldblatt was born in 1891. He pursued his medical education at the University of Michigan, where he developed an interest in pathology. After completing his medical degree, Goldblatt continued his training in pathology, which laid the foundation for his future research.

Career and Research

Goldblatt's most notable contribution to medical science was his experimental work on hypertension. In the 1930s, he conducted a series of groundbreaking experiments that demonstrated the role of the renal artery in the development of high blood pressure. By constricting the renal arteries in dogs, Goldblatt was able to induce hypertension, providing a model for studying the condition.

This work led to the identification of the renin-angiotensin system, a hormone system that regulates blood pressure and fluid balance. Goldblatt's experiments showed that reduced blood flow to the kidneys triggered the release of renin, which in turn led to the production of angiotensin, a potent vasoconstrictor. This discovery was crucial in understanding the pathophysiology of hypertension and paved the way for the development of antihypertensive drugs.

Legacy

Harry Goldblatt's contributions to the field of hypertension have had a lasting impact on medical research and treatment. His work not only provided a deeper understanding of the mechanisms of high blood pressure but also influenced the development of new therapeutic approaches. Goldblatt's research continues to be a cornerstone in the study of cardiovascular diseases.

Related Pages

• Hypertension
• Renin-angiotensin system
• Renal artery
• Pathology
• University of Michigan