Hippocampus anatomy

Hippocampal Sulcus

The Hippocampal Sulcus is a prominent anatomical feature of the brain, specifically located within the medial temporal lobe. It is a part of the limbic system, which is involved in various functions such as emotion, behavior, motivation, long-term memory, and olfaction.

Anatomy

The Hippocampal Sulcus, also known as the fissure of Sylvius, is a narrow groove that separates the dentate gyrus from the subiculum and the parahippocampal gyrus. It begins at the uncus of the hippocampus and extends posteriorly, following the curve of the hippocampus.

Function

The Hippocampal Sulcus plays a crucial role in the functioning of the hippocampus, a region of the brain that is primarily associated with memory and spatial navigation. It is involved in the formation of new memories and is also associated with learning and emotions.

Clinical Significance

Abnormalities in the Hippocampal Sulcus have been associated with various neurological and psychiatric disorders. For instance, a widened Hippocampal Sulcus has been observed in patients with Alzheimer's disease, suggesting a potential role in the pathogenesis of this condition. Similarly, changes in the morphology of the Hippocampal Sulcus have been linked to schizophrenia and epilepsy.

See Also

• Hippocampus
• Medial Temporal Lobe
• Limbic System
• Alzheimer's Disease
• Schizophrenia
• Epilepsy

References

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