Holger Stark

German structural biologist

Holger Stark in 2018

Holger Stark is a prominent German structural biologist known for his pioneering work in the field of cryo-electron microscopy (cryo-EM). He has made significant contributions to the understanding of the structure and function of large biological macromolecules.

Early Life and Education

Holger Stark was born in Germany. He pursued his higher education in the field of biochemistry and molecular biology, where he developed a keen interest in the structural analysis of biological molecules. Stark completed his doctoral studies at a leading German university, where he focused on the application of electron microscopy techniques to study the structure of complex biological systems.

Career

Stark began his career as a researcher in structural biology, quickly establishing himself as an expert in cryo-electron microscopy. His work has been instrumental in advancing the understanding of the three-dimensional structures of macromolecular complexes. Stark's research has provided insights into the mechanisms of action of various biological processes at the molecular level.

Research Contributions

Holger Stark's research has primarily focused on the development and application of cryo-EM techniques to study the structure of ribosomes, protein complexes, and other large macromolecular assemblies. His work has led to the elucidation of the structural basis of protein synthesis and the mechanisms of action of various antibiotics.

Stark has also contributed to the development of new methodologies in cryo-EM, enhancing the resolution and accuracy of structural determinations. His innovations have been widely adopted in the field, facilitating the study of complex biological systems that were previously difficult to analyze.

Awards and Honors

Throughout his career, Holger Stark has received numerous awards and honors in recognition of his contributions to structural biology. He is a member of several prestigious scientific societies and has been invited to speak at international conferences and symposia.

Current Work

Holger Stark continues to lead a research group focused on advancing cryo-EM techniques and their application to challenging biological questions. His current projects involve the study of dynamic molecular machines and the development of new computational tools for image analysis in cryo-EM.

Related Pages

• Cryo-electron microscopy
• Structural biology
• Ribosome
• Protein synthesis