IGF-1 LR3

IGF-1 LR3 is a synthetic protein and lengthened analogue of human Insulin-like Growth Factor 1 (IGF-1). It has been altered to include a 13 amino acid extension on its N-terminus and the substitution of an Arginine for the Glutamic Acid at position 3. These modifications increase the biological activity of IGF-1 LR3 and make it more resistant to degradation, thus extending its half-life.

Structure and Function

IGF-1 LR3 is similar in structure to Insulin and has a high degree of sequence homology with it. It is a single-chain polypeptide composed of 83 amino acids. The protein is highly anabolic and can promote both muscle cell hyperplasia (an increase in the number of muscle cells) and muscle cell hypertrophy (an increase in the size of muscle cells).

IGF-1 LR3 binds to the IGF-1 receptor, which is found on many cell types in many different tissues. This binding activates the receptor and triggers intracellular signaling pathways that promote cell growth, proliferation, and survival.

Applications

IGF-1 LR3 has been used in scientific research and has potential applications in medicine and sports. In research, it is often used to study the effects of IGF-1 on cell growth and survival. In medicine, it has potential applications in the treatment of growth disorders, muscle wasting diseases, and metabolic disorders. In sports, it is sometimes used as a performance-enhancing drug, although its use is banned by many sports organizations.

Safety and Side Effects

The safety and side effects of IGF-1 LR3 are not fully understood, as it is a relatively new substance and has not been extensively studied in humans. However, it is known that IGF-1 can cause hypoglycemia, and it is likely that IGF-1 LR3 can cause similar effects. Other potential side effects include increased risk of cancer, as IGF-1 can promote the growth of cancer cells, and acromegaly, a condition characterized by excessive growth of the hands, feet, and face.

Legal Status

The legal status of IGF-1 LR3 varies by country. In some countries, it is classified as a prescription drug and can only be obtained with a doctor's prescription. In other countries, it is classified as a controlled substance and its possession, sale, and use are strictly regulated.