IGHG4

Ideogram human chromosome 14

IGHG4

IGHG4 is a gene that encodes a protein known as immunoglobulin heavy constant gamma 4. This gene is located on chromosome 14 in humans. The protein produced by IGHG4 is a component of antibodies, which are essential for the immune system to recognize and neutralize foreign substances such as bacteria and viruses.

Structure

The IGHG4 gene consists of multiple exons that are transcribed and translated into the immunoglobulin heavy constant gamma 4 protein. This protein is a crucial part of the constant region of antibodies, providing structural stability and facilitating interactions with other immune cells.

Function

The primary function of the immunoglobulin heavy constant gamma 4 protein is to participate in the immune response by binding to antigens and marking them for destruction by immune cells. This process is essential for the body to defend against infections and maintain overall health.

Clinical Significance

Mutations or dysregulation of the IGHG4 gene can lead to various immune-related disorders, including autoimmune diseases and immunodeficiencies. Understanding the role of IGHG4 in these conditions is crucial for developing targeted therapies and improving patient outcomes.

Research

Research on IGHG4 continues to uncover new insights into the immune system and its role in health and disease. Scientists are investigating the specific functions of this gene and its protein product to identify potential therapeutic targets for immune-related disorders.

See Also

• Immunoglobulin
• Antibody
• Chromosome 14