Immunomodulatory

Immunomodulatory refers to the alteration of the immune response or the functioning of the immune system by the action of a drug or a substance. The term encompasses substances or drugs that can both upregulate (immunostimulatory) and downregulate (immunosuppressive) the immune system.

Mechanism of Action

Immunomodulatory drugs (IMiDs) work by modifying the activity of the immune system. They can either enhance or suppress the body's immune response, depending on the situation. IMiDs can be used to treat a variety of conditions, including autoimmune diseases, infections, and cancers.

Uses

Immunomodulatory drugs are used in a variety of medical conditions. They are commonly used in the treatment of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where they help to reduce the immune system's attack on the body's own cells. They are also used in the treatment of certain types of cancer, such as multiple myeloma, where they help to boost the immune system's ability to fight cancer cells.

Side Effects

Like all drugs, immunomodulatory drugs can have side effects. These can vary widely depending on the specific drug and the individual patient. Common side effects can include fatigue, nausea, and increased risk of infections. More serious side effects can include an increased risk of certain types of cancer.

See Also

• Immunosuppressive drug
• Immunostimulant
• Autoimmune disease
• Cancer

References

Immunomodulatory Resources
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