Loperamide/simethicone

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Loperamide/simethicone is a combination medication used to treat symptoms of diarrhea and gas respectively. The medication is available over-the-counter and is commonly used to manage symptoms of Irritable Bowel Syndrome (IBS) and other gastrointestinal disorders.

Etymology[edit | edit source]

The term "Loperamide" is derived from the Greek words "lopo" meaning "to stop" and "amide" referring to its chemical structure. "Simethicone" is derived from "silicon", the element from which it is made, and "methicone", a term used to describe various silicon-based polymers.

Composition[edit | edit source]

Loperamide/simethicone is a combination of two active ingredients. Loperamide is an opioid that works by slowing down the movement of the gut. This decreases the number of bowel movements and makes the stool less watery. Simethicone is an anti-foaming agent that helps reduce bloating, discomfort, and pain caused by excess gas in the stomach or intestines.

Usage[edit | edit source]

Loperamide/simethicone is used to treat sudden diarrhea (including traveler's diarrhea). It works by slowing down the movement of the gut. This decreases the number of bowel movements and makes the stool less watery. Loperamide is also used to reduce the amount of discharge in patients who have undergone an ileostomy. It is also used to treat ongoing diarrhea caused by inflammatory bowel disease. Simethicone helps break up gas bubbles in the gut.

Side Effects[edit | edit source]

Common side effects of Loperamide/simethicone include dizziness, drowsiness, tiredness, or constipation. If any of these effects persist or worsen, contact your doctor promptly.

Related Terms[edit | edit source]

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Contributors: Prab R. Tumpati, MD