Infantile spasms
Infantile spasms (also known as West Syndrome) is a rare and severe type of epilepsy that occurs in early childhood, typically manifesting in the first year of life. This condition is characterized by a specific type of seizure known as an infantile spasm, which can cause sudden, involuntary muscle contractions.
Symptoms[edit | edit source]
The primary symptom of infantile spasms is the occurrence of spasms. These spasms often occur upon waking or after feeding, and can be subtle or quite dramatic. They may involve a sudden bending forward and stiffening of the body, arms, and legs; or a sudden arching of the back. Other symptoms may include developmental regression, or slowing or stopping of developmental progress.
Causes[edit | edit source]
The exact cause of infantile spasms is not known. However, it is often associated with a number of conditions, including tuberous sclerosis, Down syndrome, hypoxic ischemic encephalopathy, and metabolic disorders. In some cases, no cause can be identified, a condition known as cryptogenic infantile spasms.
Diagnosis[edit | edit source]
Diagnosis of infantile spasms is based on the characteristic symptoms and electroencephalogram (EEG) findings. The EEG of a child with infantile spasms often shows a pattern known as hypsarrhythmia, which is characterized by chaotic, high-amplitude waves and spikes that are irregularly distributed.
Treatment[edit | edit source]
Treatment for infantile spasms typically involves antiepileptic drugs such as vigabatrin and corticosteroids. In some cases, a ketogenic diet, which is high in fats and low in carbohydrates, may be recommended. If a specific cause for the spasms can be identified, such as a brain tumor, treatment will also target that underlying condition.
Prognosis[edit | edit source]
The prognosis for children with infantile spasms varies. Some children may experience a reduction in seizures and improvement in developmental progress with treatment, while others may continue to have ongoing seizures and developmental problems.
See also[edit | edit source]
Infantile spasms Resources | ||
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Contributors: Prab R. Tumpati, MD