Inhibition

From WikiMD's Wellness Encyclopedia

Inhibition is a process in the body that slows down or stops certain biological reactions. In the context of neuroscience, inhibition refers to the activity of inhibitory neurons that prevent other neurons from firing. In biochemistry, inhibition refers to the slowing or stopping of a chemical reaction by a molecule that binds to an enzyme.

Neuroscience[edit | edit source]

In the field of neuroscience, inhibition is a critical aspect of the functioning of the nervous system. Inhibitory neurons, also known as interneurons, release neurotransmitters that bind to receptors on other neurons, preventing them from firing. This process is essential for the regulation of neural circuits and the prevention of excessive neuronal activity, which can lead to conditions such as epilepsy.

Biochemistry[edit | edit source]

In biochemistry, inhibition refers to the process by which a molecule, known as an inhibitor, binds to an enzyme and decreases its activity. This can occur through competitive inhibition, where the inhibitor binds to the active site of the enzyme, or non-competitive inhibition, where the inhibitor binds to a different site and changes the shape of the enzyme. Inhibition is a key mechanism in the regulation of metabolic pathways in the body.

Pharmacology[edit | edit source]

In pharmacology, inhibition is a principle used in the design of drugs. Many drugs work by inhibiting the activity of specific enzymes or receptors in the body, thereby altering physiological processes. For example, antibiotics often work by inhibiting the growth of bacteria, and antidepressants can work by inhibiting the reuptake of certain neurotransmitters in the brain.

See also[edit | edit source]

Inhibition Resources
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Contributors: Prab R. Tumpati, MD