Inositol nicotinate

Inositol nicotinate

Inositol nicotinate is a compound that is often used in the field of pharmacology as a vasodilator. It is a niacin ester of inositol, which is a type of sugar alcohol. Inositol nicotinate is also known as hexanicotinate and is often used as a slow-release form of niacin.

Chemical Structure

Inositol nicotinate is composed of a molecule of inositol and six molecules of niacin. The niacin molecules are esterified to the inositol molecule, forming a complex structure. This structure allows for the slow release of niacin into the body when ingested.

Pharmacological Uses

Inositol nicotinate is primarily used as a vasodilator, which means it helps to widen blood vessels. This can help to improve blood flow and reduce blood pressure. It is often used in the treatment of conditions such as Raynaud's disease and intermittent claudication. In addition, it is sometimes used as a treatment for high cholesterol, as niacin can help to reduce levels of bad cholesterol and increase levels of good cholesterol.

Side Effects

Like all medications, inositol nicotinate can have side effects. These can include flushing, itching, and gastrointestinal problems. However, because inositol nicotinate is a slow-release form of niacin, these side effects are often less severe than with other forms of niacin.

Research

Research into inositol nicotinate is ongoing. Some studies have suggested that it may have additional benefits, such as reducing the risk of heart disease. However, more research is needed to confirm these potential benefits and to fully understand the mechanisms by which inositol nicotinate works in the body.

See Also

• Inositol
• Niacin
• Vasodilator
• Raynaud's disease
• Intermittent claudication