Insilico
Insilico is a term used in the field of computational biology to describe biological experiments conducted in silico (in silicon), or on a computer or via computer simulation. The term is a play on the Latin phrases in vivo, in vitro, and in situ, which are commonly used in biology.
Overview[edit | edit source]
Insilico experiments are primarily used in bioinformatics, a branch of biology that uses computer science, statistics, mathematics, and engineering to analyze and interpret biological data. These experiments can involve the use of computer algorithms and models to simulate biological processes, such as protein folding, gene expression, and cell division.
Insilico experiments can also involve the use of databases and software tools to analyze biological data. For example, bioinformaticians may use insilico methods to identify genes in a DNA sequence, predict protein structure and function, and analyze gene expression data.
Applications[edit | edit source]
Insilico methods are used in a variety of applications in biology and medicine. These include:
- Drug discovery: Insilico methods can be used to identify potential drug targets, design new drugs, and predict the effects of drugs on the body.
- Genomics: Insilico methods can be used to analyze genomic data, identify genes, and predict gene function.
- Proteomics: Insilico methods can be used to analyze protein sequences and structures, and predict protein function.
- Metabolomics: Insilico methods can be used to analyze metabolic pathways and networks, and predict the effects of changes in metabolism on the body.
- Systems biology: Insilico methods can be used to model and simulate complex biological systems, such as cells, tissues, and organisms.
See also[edit | edit source]
- Computational biology
- Bioinformatics
- Systems biology
- Drug discovery
- Genomics
- Proteomics
- Metabolomics
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD