Insufflation (medicine)

Insufflation (medicine) is a method of drug administration where a substance is introduced into the body via the nasal passage. This method is often used for medications that need to be rapidly absorbed into the bloodstream.

Method

Insufflation involves the inhalation of a powdered substance through the nostrils. The substance is absorbed by the mucous membranes lining the nasal passage and quickly enters the bloodstream. This method is often used for drugs that are not easily absorbed through the digestive system, or for drugs that need to be rapidly absorbed for immediate effect.

Uses

Insufflation is commonly used in the administration of recreational drugs, such as cocaine and ketamine. However, it is also used in medical settings for the administration of certain medications. For example, nasal sprays containing decongestants or corticosteroids are often administered via insufflation to treat conditions such as allergic rhinitis.

Risks

While insufflation can allow for rapid drug absorption, it also carries certain risks. The nasal passage is delicate and can be easily damaged by repeated insufflation. This can lead to conditions such as nosebleeds, nasal septum perforation, and chronic sinusitis. Additionally, some substances may cause an immediate and severe reaction if insufflated, such as anaphylaxis.

See Also

• Inhalation
• Drug administration
• Nasal spray