Interleukin-1-alfa

Interleukin-1-alfa is a type of cytokine, a group of proteins made by the immune system. Cytokines are responsible for cell signaling, and they can stimulate the immune system to fight disease. Interleukin-1-alfa is produced by various types of cells, including macrophages, dendritic cells, and B cells. It plays a crucial role in the regulation of immune and inflammatory responses to infections or sterile insults.

Function

Interleukin-1-alfa is involved in various immune responses, inflammatory processes, and hematopoiesis (the formation of blood cellular components). It is a potent proinflammatory cytokine that can produce fever, inflammation, tissue destruction, and, in some cases, shock and death.

Clinical Significance

Interleukin-1-alfa has been implicated in a variety of diseases, including rheumatoid arthritis, Alzheimer's disease, and cancer. It is also involved in the inflammatory response to injury and infection. In cancer, it may promote tumor growth and progression.

Therapeutic Use

Interleukin-1-alfa has been used therapeutically in the treatment of certain types of cancer, including renal cell carcinoma and melanoma. It is also being investigated for its potential use in the treatment of other diseases, such as autoimmune diseases and inflammatory bowel disease.

See Also

• Interleukin
• Cytokine
• Immune system
• Inflammation

Interleukin-1-alfa Resources
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